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OGRL works independently or collaboratively to pair fate and transport with biological experiments and effects. OGRL has three main focuses: 1. Development and modification of robust analytical methods needed for analysis of compounds in multiple matrices to address relevant environmental health issues. Conduct independent and collaborative lab to national based studies to provide new knowledge on source to receptor pathways for potential environmental relevant organic contaminants. Conduct collaborative research to study correlations between individual compound and environmental mixture and environmental health effects. Hot Topics • A team of scientists from the USGS and the Agroscope Reckenholz-Tanikon Research Station, Switzerland, found that some mycotoxins are common in U.S. Stream waters. () • Measuring POEA, a Surfactant Mixture in Herbicide Formulations.

() • Groundwater microbial community composition affected during 30-day exposure to sub mg/L concentrations of the antibiotic, sulfamethoxazole. • Two microbial communities from a sandy aquifer, one acclimated historically to wastewater with sulfamethoxazole and the other unacclimated were exposed to in situ 240-520 μg/L sulfamethoxazole using filter chambers suspended ambient groundwater for 30 days. The unacclimated microbial community displayed greater changes in mortality and impairment, sensitivity to sulfamethoxazole, and community composition than the unacclimated microbial community. The study shows that microbial communities can be affected by concentrations 2-3 orders of magnitude less than those used in clinical applications. Sample Processing Samples will be collected using protocols for the collection of pesticide analysis in Shelton, (1994) • Preclean all equipment with a Liquinox/tap-water solution, rinsed with tap water, deonized water, and then methanol, and then air dry. • Filter sample water through a 0.7-µm pore-size baked glass-fiber filter after a 100 ml rinse of the filter with sample water, into 125-ml (4 oz) baked amber glass bottles (If filtering is not possible, then it can be done upon request at a rate of $30 persample). • Upon collection, all samples will be kept chilled until shipped to the lab.

Shipping Instructions Label bottles clearly with waterproof marker or preprinted labels (a paper label completely covered with clear packing tape is preferred). Year Published: 2004 A proof-of-concept experiment was devised to determine if pharmaceuticals and other organic waste water compounds (OWCs), as well as pathogens, found in treated effluent could be transported through a 2.4 m soil column and, thus, potentially reach ground water under recharge conditions similar to those in arid or semiarid climates. Cordy, Gail E.; Duran, Norma L.; Bouwer, Herman; Rice, Robert C.; Furlong, Edward T.; Zaugg, Steven D.; Meyer, Michael T.; Barber, Larry B.; Kolpin, Dana W. Year Published: 2004 Ground water samples collected from the Norman Landfill research site in central Oklahoma were analyzed as part of the U.S. Geological Survey (USGS) Toxic Substances Hydrology Program's national reconnaissance of pharmaceuticals and other organic waste water contaminants (OWCs) in ground water. Five sites, four of which are located downgradient of. Barnes, Kimberlee K.; Christenson, Scott C.; Kolpin, Dana W.; Focazio, Michael J.; Furlong, Edward T.; Zaugg, Steven D.; Meyer, Michael T.; Barber, Larry B.